True. Only with 200% (or close to) looks OK. Try global MEDIUM with Ultra Foliage and some increase of screen percentage.
Here's how I have my settings: Screen Resolution: 3840x2160 (4K) Graphics Preset: Ultra AA: Off Screen Percentage: 100% I still get a degree of flickering with this but FXAA doesn't look like it makes a difference at this resolution and TAA looks a little... blurry to me? Blurry is the best word I can think of to describe it. I usually only notice flickering on overhead lines and even then it doesn't bother me. My fps usually ranges from 50-60fps, areas where it goes lower usually turn out to be the game rather than my laptop such as Munich where I get about 20fps until leave the area. Hopefully all of these optimisations that DTG are doing will change that in the future
It's nothing to do with TSW but a fact of computing: higher resolution means more horsepower is needed.