I was trying to do Amtrak Northeast Regional #66 Boston-Depot and when you reverse into Southampton yard it makes you go into a building and yeah
I had this but on one of the scenarios, only that time the building was no clip so I drove straight through and continued on to complete the scenario
I also have the same issue. I was doing the Journey and it was scenario 15 for me. I tried numerous different attempts. Made sure all the switches were lined correctly and the train derailed just before the building. Then tried leaving the switches alone and I could make it half way through the building and it derailed. Another time I stopped short of the spur that leads into the building to check the map to make sure I was on the correct highlighted route ( I was) and while sitting there stopped the train derailed.