I’m looking how to set up all the options in game to be as pro as possible. I’m just now am getting into trains. Thanks ahead for the help.
I guess the most "pro" option would be to drive with the HUD turned completely off. ;-) I do that on the Class 66 which is probably about as realistic as it can get. The good thing about driving the 66 is that there's no timetable so you don't need the clock and you only have to be aware of speeding around junctions and stations.
Yes the most pro/realistic/sim way to play would indeed be to turn the HUD off completely. If you decided to do this here are some incredibly useful links for you. British Signalling Guide - German Signalling Guide - Great Western Main Line Route Guide (Reading to London Paddington) - Leipzig S-Bahn Route Guide (Dessau to Markkleeberg) - Enjoy!
You can also attach a USB keyboard to your console and press F1 to turn everything on the screen off (great for screen shots). The nice thing about the keyboard is that you can quickly press F1 to get everything back if you need to check the time or a speed limit or similar.