It would have to come down to a party other than BNSF for locomotives. DTG will not touch BNSF now because of the restricted license and not liking to not use the livery, while other developers don't mind (see the new Arizona route announced in fact) and livery designers can easily just create a livery adding the missing trademark to make the official train, which can then be swapped into the scenarios. No harm to DTG that way while still sold on Steam. Some BNSF stuff is appearing third-party, such as Travel By Train, but on Steam any actual new BNSF will most likely not appear from DTG directly. So the question becomes whether CN, CSX, or anyone else uses the track besides BNSF to warrant DTG possibly visiting it for a US DLC on their part. It looks like mainly BNSF, so that would be that if so. Finally, it's a 210 mile route. That's way too long for one DLC. I can tell you right now you would probably want to focus on a segment of the route that has significance, likely less than 100 miles. Is there a portion that stands out, and why?
It seems that Union Pacific and Norfolk Southern also using the route so mabye could use Union Pacific and/or Norfolk Southern when doing that route?
If it's Norfolk Southern perhaps length of the route should be around 90 to 120 miles maybe across city locations in states like Georgia or Kentucky