PC Game Won't Respond To Open Door Keybinds After Spad And Load Last Checkpoint

Dresden-Riesa, BR143, I wasn't paying attention and did a SPAD. I loaded the last checkpoint and all was fine, until at the next station the game didn't respond to the Y and U keybinds, neither did it respond to opening the doors via the TAB-menu.

Fortunately I remembered seeing Matt opening the doors via the in-cab controls and was able to open (and close) the doors via the in-cab buttons, so that works.

Now I also remember running into similar problems on the Isle of Wight, so I think it's a problem that affects multiple routes.