I no longer seem to be able to select Quick Drive on several routes, including Welsh Marshes and Cornish Main Line (both from Steam). I have done a verify local files. I _know_ I have ran QDs on both routes before, so this seems to be something that happened post-TS2021...
To get them back do this, it worked for me. Go to Content in your Railworks folder. Delete SDBC Cache Bin Delete SDBC Cache Bin MDS Fire up TS and your lost routes will magically reappear.